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[22] Refrigeration is not strictly required but may prolong shelf life if temperature excursions are common

Atwood, Kimball (4 November 2012)

As a result, when the vial thaws, the benzyl alcohol is no longer evenly distributed throughout the solution you may end up with concentrated pockets and diluted areas

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(As a side note, one way that cells can enter senescence is by telomere shortening

It is classified as a Category 2 bulk drug substance by the FDA, which restricts its availability through compounding pharmacies